Start with a single cell. Shorten the path to development.

Visual, low-damage single-cell manipulation connects cell loading, functional validation, screening, recovery and downstream analysis.
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ANTIBODY DRUG DEVELOPMENT

Link antibody function to sequence, cell by cell.

Import and isolate individual B cells, validate the secreted antibodies, then recover high-specificity cells for sequencing and bioinformatics analysis.

Antibody drug development at single-cell resolutionANTIBODY DRUG DEVELOPMENT / CHIPLIGHT

WORKFLOW OVERVIEW

Individual B cells are imported and isolated before their secreted antibodies undergo functional validation. Affinity and specificity against the target protein are evaluated to identify and recover high-specificity B cells.

Downstream sequencing and bioinformatics link each cell’s sequence data directly with its measured antibody function, producing antibody sequences with traceable functional evidence.

OptoBot® 1000 microwells are approximately one hundred-thousandth the volume of a 384-well plate. Media exchange supports long-term cell culture and can shorten the overall development cycle by two months.

Discuss your workflow
UP TO2 months faster
MICROWELL VOLUME1 / 100,000
OUTPUTFunction-linked sequences

WORKFLOW

A traceable path from cell to result
01Import & isolate single B cells
02Validate antibody function
03Assess affinity & specificity
04Recover high-specificity cells
05Sequence & analyze
06Match function to sequence